Yes. Just because Wine runs on a non-Windows OS doesn't mean you're protected from viruses, trojans, and other forms of malware.

Wine is a compatibility layer that allows running Windows applications on Unix-like operating systems, such as Linux and macOS. It is not inherently designed to be "malware-compatible," and it doesn't facilitate the execution of malware by default.

However, it's important to note that any environment that allows running executable code, including Wine, can potentially be exploited. If you run Wine and install Windows applications from untrusted or malicious sources, there is a risk of running malware. The security of your system depends on various factors, including your actions, the applications you install, and how well you maintain your system.

To minimize security risks:

1. **Use Official Sources:** Download Wine from official sources to ensure you are getting a legitimate and secure version.

2. **Install Trusted Software:** Only install Windows applications from reputable and trusted sources.

3. **Regular Updates:** Keep your Wine installation and your operating system up-to-date with the latest security patches.

4. **Security Software:** Consider using antivirus or anti-malware software to add an extra layer of protection.

5. **Configure Wine Properly:** Understand Wine's configuration options and adjust them as needed. For example, you can create separate Wine prefixes for different applications to isolate them.

Remember that no system is entirely risk-free, and it's crucial to adopt security best practices to minimize potential vulnerabilities.